GDC-9918
GDC-9918 (compund GDC-9918) is a Janus kinase inhibitor[1].
Product Specifications
CAS Number
[2570375-06-1]
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gdc-9918.html
Smiles
O=C(C1=C2N=CC=CN2N=C1)NC3=CN(C)N=C3C4=CC(S(=O)(CCO)=O)=CC=C4OC(F)F
Molecular Formula
C20H18F2N6O5S
Molecular Weight
492.46
References & Citations
[1]Dalton D M, et al. Development of a Robust Pd-Catalyzed C–S Coupling for the Synthesis of Janus Kinase Inhibitor GDC-9918[J]. Organic Process Research & Development, 2024, 28 (10) : 3858-3870.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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