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ISIS 449884

ISIS 449884 is a 2'-O-methoxyethyl antisense oligonucleotide that targets GCGR. ISIS 449884 has an ability to reduce hepatic glucose output and lower the blood glucose level. ISIS 449884 can be used for the study of type 2 diabetes mellitus (T2DM) [1].

Product Specifications

CAS Number

1428588-67-3

UNSPSC

12352208

Target

GCGR

Type

Oligonucleotides

Related Pathways

GPCR/G Protein

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/isis-449884.html

Smiles

[ISIS449884]

References & Citations

[1]Linong Ji, et al. ISIS 449884 Injection Add-On to Metformin in Patients with Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Phase II Clinical Study. Diabetes Ther. 2024 Oct;15 (10) :2183-2196.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Frequently Asked Questions

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