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3'-Deoxy-3'-fluoroadenosine

3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

CAS Number

75059-22-2

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H332, H335

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others; Cancer

Assay Protocol

https://www.medchemexpress.com/3-deoxy-3-fluoroadenosine.html

Purity

99.29

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC[C@H]1O[C@@H](N(C=N2)C3=C2C(N)=NC=N3)[C@H](O)[C@@H]1F

Molecular Formula

C10H12FN5O3

Molecular Weight

269.24

Precautions

H302, H315, H319, H332, H335

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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