Lonicerin

Lonicerin (Veronicastroside) is a flavonoid with multiple biological activities. Lonicerin inhibits xanthine oxidase with an IC50 of 37.4 µg/mL. Lonicerin inhibits alginate secretion protein (AlgE) . Lonicerin inhibits P. aeruginosa and C. albicans. Lonicerin has anti-inflammatory, anti-arthritic, antioxidant, antifungal, anti-bacterial, and neuroprotective properties[1][2][3].

Product Specifications

CAS Number

[25694-72-8]

Product Name Alternative

Veronicastroside

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Bacterial; Fungal; Xanthine Oxidase

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/lonicerin.html

Purity

99.77

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C1C2=C(O)C=C(O[C@H]3[C@@H]([C@H]([C@H](O)[C@@H](CO)O3)O)O[C@@]4([H])[C@@H]([C@@H]([C@@H](O)[C@H](C)O4)O)O)C=C2OC(C5=CC(O)=C(O)C=C5)=C1

Molecular Formula

C27H30O15

Molecular Weight

594.52

Precautions

H302, H315, H319, H335

References & Citations

[1]Xu Z, et al. Lonicerin, an anti-algE flavonoid against Pseudomonas aeruginosa virulence screened from Shuanghuanglian formula by molecule docking based strategy. J Ethnopharmacol. 2019 Jul 15;239:111909.|[2]Lee JH, et al. Antiarthritic effect of lonicerin on Candida albicans arthritis in mice. Arch Pharm Res. 2011 May;34 (5) :853-9. |[3]Xiao Ding, et al. Evaluation of Anti-MRSA and Xanthine Oxidase Inhibition Activities of Phenolic Constituents from Plumula nelumbinis. Journal of Chemistry. 24 December 2015.