11-dehydro-2,3-dinor Thromboxane B2
11-dehydro-2,3-dinor Thromboxane B2 (11-dehydro-2,3-dinor TXB2) is a metabolite of the TXA2 inactive metabolite TXB2 (Item No. 19030) . It is formed from TXB2 by cytosolic aldehyde dehydrogenase (ALDH) and β-oxidation. Levels of 11-dehydro-2,3-dinor TXB2 are increased 5.2-fold in a surgery-induced rat model of tendon overuse.
Product Specifications
CAS Number
[79250-60-5]
Product Name Alternative
11-dehydro-2,3-dinor TXB2
UNSPSC
12352005
Hazard Statement
H225, H319, H336
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/11-dehydro-2-3-dinor-thromboxane-b2.html
Concentration
293.76 μM * 100 μL in Methyl acetate
Purity
99.0
Smiles
O[C@@H]1[C@@H]([C@H](OC(C1)=O)/C=C/[C@@H](CCCCC)O)C/C=C\CC(O)=O
Molecular Formula
C18H28O6
Molecular Weight
340.41
Precautions
H225, H319, H336
References & Citations
[1]Roberts, et al. Metabolism of thromboxane B2 in Man. Identification of the major urinary metabolite. J. Biol. Chem. 256 (16), 8384-8393 (1981) .
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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