Mycro 3
Mycro 3 is an orally active, potent and selective inhibitor of Myc-associated factor X (MAX) dimerization. Mycro 3 also inhibit DNA binding of c-Myc[1]. Mycro 3 could be used for the research of pancreatic cancer[2].
Product Specifications
CAS Number
[944547-46-0]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Autophagy; c-Myc
Type
Reference compound
Related Pathways
Apoptosis; Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Mycro_3.html
Purity
98.11
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(C1=C(NC(C2=NN3C(C(F)(Cl)F)=CC(C4=CC=CO4)=NC3=C2)=O)N(C5=CC=CC=C5)N=C1)OCC
Molecular Formula
C24H17ClF2N6O4
Molecular Weight
526.88
Precautions
H315, H319, H335
References & Citations
[1]Chen BJ, et al. Small molecules targeting c-Myc oncogene: promising anti-cancer therapeutics. Int J Biol Sci. 2014 Sep 13;10 (10) :1084-96.|[2]Dimitris Stellas, et al. Therapeutic effects of an anti-Myc drug on mouse pancreatic cancer. J Natl Cancer Inst. 2014 Oct 11;106 (12) :dju320.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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