(-) -Vesamicol

(-) -Vesamicol (AH5183) is an inhibitor of acetylcholine transport into synaptic vesicles, with the IC50 of 75 nM[1]. (-) -Vesamicol can be used for release and recycling of synaptic vesicles study[1].

Product Specifications

CAS Number

[112709-59-8]

Product Name Alternative

AH5183

UNSPSC

12352005

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/minus-vesamicol.html

Purity

99.35

Solubility

DMSO : 12.5 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@H](N2CCC(C3=CC=CC=C3)CC2)CCCC1

Molecular Formula

C17H25NO

Molecular Weight

259.39

References & Citations

[1]Searl T, et al. Acetylcholine recycling and release at rat motor nerve terminals studied using (-) -vesamicol and troxpyrrolium. J Physiol. 1991;444:99-116.