(-) -Vesamicol
(-) -Vesamicol (AH5183) is an inhibitor of acetylcholine transport into synaptic vesicles, with the IC50 of 75 nM[1]. (-) -Vesamicol can be used for release and recycling of synaptic vesicles study[1].
Product Specifications
CAS Number
112709-59-8
Product Name Alternative
AH5183
UNSPSC
12352005
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/minus-vesamicol.html
Purity
99.35
Solubility
DMSO : 12.5 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@H](N2CCC(C3=CC=CC=C3)CC2)CCCC1
Molecular Formula
C17H25NO
Molecular Weight
259.39
References & Citations
[1]Searl T, et al. Acetylcholine recycling and release at rat motor nerve terminals studied using (-) -vesamicol and troxpyrrolium. J Physiol. 1991;444:99-116.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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