7-Chlorokynurenic acid (sodium salt)
Selected Variant
HY-100811A-01
Size: 5 mg
7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM) . 7-Chlorokynurenic acid sodium salt is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid sodium salt has potent antinociceptive actions after neuraxial delivery[1][2].
Product Specifications
CAS Number
1263094-00-3
Product Name Alternative
7-CKA (sodium salt)
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/7-Chlorokynurenic_acid_sodium_salt.html
Purity
99.89
Solubility
DMSO : ≥ 33.67 mg/mL|H2O : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=NC2=CC(Cl)=CC=C2C(O)=C1)O[Na]
Molecular Formula
C10H5ClNNaO3
Molecular Weight
245.59
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor
Available Sizes
Price
Frequently Asked Questions
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