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TLE 1 Recombinant Rabbit Monoclonal Antibody [JE41-40]

Selected Variant

HA722702

Size: 100 µL

Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. Enhances FOXG1/BF-1- and HES1-mediated transcriptional repression (By similarity). The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

E (Sp1) homolog antibody Enhancer of split groucho 1 antibody Enhancer of split groucho like protein 1 antibody Enhancer of split groucho-like protein 1 antibody ESG antibody ESG1 antibody GRG1 antibody TLE1 antibody TLE1_HUMAN antibody Transducin like enhancer of split 1 (E (sp1) homolog Drosophila) antibody Transducin like enhancer of split 1 antibody Transducin like enhancer of split 1 homolog of Drosophila E (sp1) antibody Transducin like enhancer protein 1 antibody Transducin-like enhancer protein 1 antibody

Abbreviation

TLE1

Swiss Prot

Q04724 Human, Q62440 Mouse,

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within

Isotype

IgG

Clone

JE41-40

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P

Positive Control

293T cell lysate, HepG2 cell lysate, Jurkat cell lysate, SH-SY5Y cell lysate, Human lung tissue lysate, Mouse lung tissue lysate, Rat lung tissue lysate, 293T, human colon tissue, mouse lung tissue, rat lung tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IF-Cell: 1:50 ;IHC-P: 1:50

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 83 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

Price

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