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PathoGreenTM Histofluorescent Neurodegeneration Dye

Our PathoGreenTM Histofluorescent Neurodegeneration Dye is functionally similar to Fluoro-Jade® dye. It stains degenerating neurons and their processes after exposure to a variety of neurotoxic insults in brain sections and cultured neurons.

Product Specifications

Background

PathoGreenTM Histofluorescent Stain is an anionic green fluorescent dye functionally similar to Fluoro-Jade dyes. These dyes stain degenerating neurons and their processes after exposure to a variety of neurotoxic insults in brain sections and cultured neurons. The mechanism of neuronal staining by anionic fluorescent dyes has not been determined. It has been proposed that the negatively charged dyes bind to positively charged polyamines or other molecules specifically generated in dying neurons.

Type

Dyes & Tracing Reagents

Applications

ICC, IHC, EM

Concentration

1000X

Format

1000X in water

Buffer

1000X in water

Shipping Conditions

Shipped at ambient temperature with desiccant; protected from light

Storage Conditions

Store at –20°C, with desiccant; protect from light.

Specificity

For use in fixed cells and tissue sections.

Recommended Usage

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Physical Properties

Solution

Conjugate

Ex: 497 nm, Em: 520 nm

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