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Methotrexate, CF®640R Conjugate

Our CF®640R conjugated methotrexate is a cytotoxic agent that induces cell cycle arrest and is useful for studying antimetabolite resistance, spontaneous gene amplification, cell uptake and drug binding.

Product Specifications

Background

Methotrexate is a cytotoxic agent that is actively taken up by cells and binds to and inhibits dihydrofolate reductase, thereby inhibiting folic acid metabolism and inducing cell cycle arrest. It is useful for studying antimetabolite resistance, spontaneous gene amplification, cell uptake and drug binding. Conjugated to CF® 640R dye.

Type

Dyes & Tracing Reagents

Applications

ICC, IHC, EM

Shipping Conditions

Shipped at ambient temperature; protected from light

Storage Conditions

Store at –20°C, protect from light.

Recommended Usage

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Physical Properties

Solid

Conjugate

CF®640R Ex: 642 nm, Em: 662 nm

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