Methotrexate, CF®594 Conjugate
Our CF®594 conjugated methotrexate is a cytotoxic agent that induces cell cycle arrest and is useful for studying antimetabolite resistance, spontaneous gene amplification, cell uptake and drug binding.
Product Specifications
Background
Methotrexate is a cytotoxic agent that is actively taken up by cells and binds to and inhibits dihydrofolate reductase, thereby inhibiting folic acid metabolism and inducing cell cycle arrest. It is useful for studying antimetabolite resistance, spontaneous gene amplification, cell uptake and drug binding. Conjugated to CF® 594 dye.
Type
Dyes & Tracing Reagents
Applications
ICC, IHC, EM
Shipping Conditions
Shipped at ambient temperature; protected from light
Storage Conditions
Store at –20°C, protect from light.
Recommended Usage
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
Physical Properties
Solid
Conjugate
CF®594 Ex: 593 nm, Em: 614 nm
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