What is the catalog number for Alpha-Bungarotoxin?

The catalog number for Alpha-Bungarotoxin is 81-1200.

What sizes are available for Alpha-Bungarotoxin?

Alpha-Bungarotoxin is available in the following size(s): 1 mg.

Is Alpha-Bungarotoxin in stock?

Alpha-Bungarotoxin is currently made to order / not held in immediate stock. Contact us for lead time.

Alpha-Bungarotoxin

Our alpha-Bungarotoxin is a potent neurotoxin widely used to study neuromuscular junctions by blocking cholinergic receptors. Membrane impermeant, it works well in live/intact cells and cells fixed in formaldehyde or methanol.

Product Specifications

Background

Alpha-Bungarotoxin is a high affinity inhibitor (Kd = 1 nM to 1 pM) of the nicotinic acetylcholine receptor in the neuromuscular junction and blocks acetylcholine activity at the postsynaptic membrane. It is often used to study neuromuscular junctions by blocking cholinergic receptors. The effects of α-bungarotoxin on neuronal nAChR have been shown to be highly specific for the α7-subtype (IC50 = 1.6 nM), but not for the α3β4-subtype (IC50 >3 μM) . Labeled α-bungarotoxin conjugates can be used for staining nicotinic acetylcholine receptors at neuromuscular junctions in tissue sections.

Synonyms

Neurotoxin, nicotinic (a7) receptor antagonist

Type

Dyes & Tracing Reagents

Applications

ICC, IHC, EM

Molecular Weight

7984 Da

Shipping Conditions

Shipped at ambient temperature with desiccant

Storage Conditions

Store at –20°C, with desiccant.

Specificity

Membrane impermeant; works in live/intact cells and cells fixed in formaldehyde or methanol.

Recommended Usage

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.