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Anti-c-FOS Antibody

Our Anti-c-FOS mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N486/32. It detects human, mouse, and rat c-FOS, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Product Specifications

Background

C-fos belongs the Fos family. Other members include FosB, Fra-1, Fra-2. c-fos binds to JUN/AP1 transcription factor. C-Fos is expressed in placental tissue, fetal liver, developing bone, developing central nervous system, and adult bone marrow. It is expressed in the nucleus and in the endoplasmic reticulum. c-Fos is has a role in signal transduction, cell proliferation, differentiation, and apoptosis. C-Fos is overexpressed in many cancers.

Short Description

Our Anti-c-FOS mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N486/32. It detects human, mouse, and rat c-FOS, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

Proto-oncogene c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7

Gene Name

FOS, G0S7

UniProt

P01100

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 1-377 (full-length) of human FOS (accession number P01100) produced recombinantly in E. Coli

Target

C-FOS

Clonality

Monoclonal

Isotype

IgG2a

Clone

N486/32

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Oncoproteins/Transcription Regulation

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

70 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when tested by Western Blot.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

WB Quality Control

1

Conjugate

Unconjugated

RRID

AB_2927659

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