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Anti-SAPAP3 Antibody FL490 Conjugate

Our Anti-SAPAP3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L126/93. It detects mouse and rat SAPAP3, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Disks large-associated protein 3, SAP90/PSD-95-Associated Protein 3 or SAPAP3 is encoded by the gene DLGAP3 and is a member of the SAPAP or DLGAP family of proteins. SAPAP3 acts as a scaffold protein and is involved with glutamate receptor signaling. SAPAP3 is highly expressed in the central and peripheral nervous system. Within the cell, SAPAP3 is found at the postsynaptic density. Diseases associated with DLGAP3 include Trichotillomania and Body Dysmorphic Disorder.

Short Description

Our Anti-SAPAP3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L126/93. It detects mouse and rat SAPAP3, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

SAPAP3, Disks large- associated protein 3, PSD 95/SAP90-binding protein 3, SAP90/PSD-95 associated protein

Gene Name

Dlgap3, Dap3

UniProt

Q6PFD5

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 790-977 (C-terminus) of mouse SAPAP3 (accession number Q6PFD5) produced recombinantly in E. Coli

Target

SAPAP3

Clonality

Monoclonal

Isotype

IgG2b

Clone

L126/93

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Glutamate Receptors/Scaffold Proteins

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

110 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with SAPAP2/DLGAP2 and other SAPAP/DLGAP proteins

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

WB Brain Quality Control

1

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

RRID

AB_2940672

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