α-Lipoic acid-NHS
α-Lipoic acid-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[40846-94-4]
Product Name Alternative
DL-α-Lipoic acid-NHS
UNSPSC
12352005
Hazard Statement
H315, H319, H372, H410
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/α-lipoic-acid-nhs.html
Purity
98.0
Solubility
Ethanol : 2 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(ON1C(CCC1=O)=O)CCCCC2SSCC2
Molecular Formula
C12H17NO4S2
Molecular Weight
303.40
Precautions
H315, H319, H372, H410
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers
Available Sizes
Curated Selection
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