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Anti-Kir2.4 Antibody

Our Anti-Kir2.4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N465/11. It detects mouse and rat Kir2.4, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

ATP-sensitive inward rectifier potassium channel 14 or Kir1.4 is encoded by the gene KCNJ14. Kir2.4 is a member of the inward rectifier potassium ion channel family and plays a role controlling the resting membrane potential in muscle cells and neurons. Kir2.4 is an integral membrane protein that is expressed in neuronal cells of the cranial nerve, motor nuclei in the midbrain, pons, and medulla.

Short Description

Our Anti-Kir2.4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N465/11. It detects mouse and rat Kir2.4, and is purified by protein a chromatography. It is great for use in IHC, ICC, ELISA.

Synonyms

Kir2.4 (ATPsensitive inward rectifier potassium channel 14) (Potassium channel, inwardly rectifyingsubfamily J member 14) (Kcnj14) (Irk4)

Gene Name

Kcnj14 Irk4

UniProt

Q8JZN3

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 360-434 (cytoplasmic C-terminus) of mouse Kir2.4 (accession number Q8JZN3) produced recombinantly in E. Coli

Target

Kir2.4

Clonality

Monoclonal

Isotype

IgG1

Clone

N465/11

Type

Primary Antibody

Applications

IHC, ICC, ELISA

Field of Research

Ion Channels and Modulators/K+ Channels

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

47 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

Conjugate

Unconjugated

IHC Quality Control

1

RRID

AB_2722671

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