Anti-MiRP4 Antibody FL650 Conjugate

Potassium voltage-gated channel subfamily E regulatory subunit 5 is encoded by the gene KCNE5. KCNE5 is a member of the potassium channel KCNE family. KCNE5 is a potassium channel ancillary subunit that is essential for generation of some native K (+) currents by forming a heteromeric ion channel complex with voltage-gated potassium (Kv) channel pore-forming alpha subunits. KCNE5 functions as an inhibitory beta-subunit of the repolarizing cardiac potassium ion channel KCNQ1. KCNE5 is expressed in the heart, skeletal muscle, brain, spinal cord, and placenta. Diseases associated with KCNE5 include brugada syndrome and alport syndrome-intellectual disability-midface hypoplasia-elliptocytosis syndrome.

Our Anti-MiRP4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N472/88. It detects human, mouse, and rat MiRP4, and is purified by protein a chromatography. It is great for use in ICC.

MiRP4 (Potassium channel subunit beta MiRP4) (Potassium voltagegatedchannel subfamily E regulatory beta subunit 5) (Voltage-gated potassium channelaccessory subunit 5) (AMME syndrome candidate gene 2 protein) (Potassium voltage-gatedchannel subfamily E member 1-like protein) (MinK-like protein)

Fusion protein amino acids 1-60 (extracellular N-terminus) and 82-142 (cytoplasmic C-terminus) of human MiRP4 (accession number Q9UJ90) produced recombinantly in E. Coli

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.