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Anti-MiRP4 Antibody

Our Anti-MiRP4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N472/88. It detects human, mouse, and rat MiRP4, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Product Specifications

Background

Potassium voltage-gated channel subfamily E regulatory subunit 5 is encoded by the gene KCNE5. KCNE5 is a member of the potassium channel KCNE family. KCNE5 is a potassium channel ancillary subunit that is essential for generation of some native K (+) currents by forming a heteromeric ion channel complex with voltage-gated potassium (Kv) channel pore-forming alpha subunits. KCNE5 functions as an inhibitory beta-subunit of the repolarizing cardiac potassium ion channel KCNQ1. KCNE5 is expressed in the heart, skeletal muscle, brain, spinal cord, and placenta. Diseases associated with KCNE5 include brugada syndrome and alport syndrome-intellectual disability-midface hypoplasia-elliptocytosis syndrome.

Short Description

Our Anti-MiRP4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N472/88. It detects human, mouse, and rat MiRP4, and is purified by protein a chromatography. It is great for use in WB, ICC, ELISA.

Synonyms

MiRP4 (Potassium channel subunit beta MiRP4) (Potassium voltagegatedchannel subfamily E regulatory beta subunit 5) (Voltage-gated potassium channelaccessory subunit 5) (AMME syndrome candidate gene 2 protein) (Potassium voltage-gatedchannel subfamily E member 1-like protein) (MinK-like protein)

Gene Name

KCNE5 AMMECR2 KCNE1L RCG23148

UniProt

Q9UJ90

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 1-60 (extracellular N-terminus) and 82-142 (cytoplasmic C-terminus) of human MiRP4 (accession number Q9UJ90) produced recombinantly in E. Coli

Target

MiRP4

Clonality

Monoclonal

Isotype

IgG2a

Clone

N472/88

Type

Primary Antibody

Applications

WB, ICC, ELISA

Field of Research

Ion Channels and Modulators/K+ Channels

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

Unconjugated

RRID

AB_2722669

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