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Anti-SAPAP1 Antibody FL650 Conjugate

Our Anti-SAPAP1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N238/30. It detects human, mouse, and rat SAPAP1, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

SAPAP1 (also known as disks large associated protein 1, DAP-1, or DLGAP1) is a member of the SAPAP or DLGAP family of proteins. SAPAP1 is part of the scaffold in neuronal cells of the brain and is a component of the postsynaptic complex. SAPAP1 acts as an adaptor protein that binds synaptic scaffold proteins, cytoskeletal proteins and signaling proteins including PSD-95 and SHANK. SAPAP1 is expressed in neurons of the cortex, hippocampus and in Purkinje cells in the cerebellum. Diseases associated with DLGAP1 include Retinitis Pigmentosa 55 and Obsessive-Compulsive Disorder

Short Description

Our Anti-SAPAP1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N238/30. It detects human, mouse, and rat SAPAP1, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Disks large-associated protein 1 (SAPAP1) SAPAP-1

Gene Name

DLGAP1 DAP1 GKAP

UniProt

P97836

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 772-992 (C-terminus) of rat SAPAP1 (accession number P97836) produced recombinantly in E. Coli

Target

SAPAP1

Clonality

Monoclonal

Isotype

IgG1

Clone

N238/30

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Scaffold Proteins

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

110 kDa (varies due to post-translational modifications)

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

IHC Quality Control

1

RRID

AB_2940563

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