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Anti-TrpM6 Antibody FL594 Conjugate

Our Anti-TrpM6 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N470/22. It detects human TrpM6, and is purified by Protein A chromatography. It is great for use in ICC.

Product Specifications

Background

Transient receptor potential cation channel subfamily M member 6 or TrpM6 is encoded by the gene TRPM6. TrpM6 is a member of the transient receptor potential ion channel family and acts as a serine/threonine-protein kinase. TrpM6 has an essential function in magnesium transport and is involved with magnesium absorption in the gut and kidney. TRPM6 is primarily expressed in the kidney, colon, GI tract and placenta kidney. Mutations in this gene are associated with hypomagnesemia with secondary hypocalcemia.

Short Description

Our Anti-TrpM6 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N470/22. It detects human TrpM6, and is purified by protein a chromatography. It is great for use in ICC.

Synonyms

TrpM6 (Transient receptor potential cation channel subfamily M member 6) (Melastatin-related TRPcation channel 6) (Channel kinase 2)

Gene Name

TRPM6 CHAK2

UniProt

Q9BX84

Host

Mouse

Reactivity

Human

Immunogen

Fusion protein amino acids 1258-1480 (cytoplasmic C-terminus) of human TrpM6 (accession number Q9BX84) produced recombinantly in E. Coli

Target

TrpM6

Clonality

Monoclonal

Isotype

IgG2a

Clone

N470/22

Type

Primary Antibody

Applications

ICC

Field of Research

Ion Channels and Modulators/Trp Channels

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

240 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

FL594 Ex: 594 nm, Em: 615 nm

RRID

AB_2940550

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