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Anti-THIK-2 Antibody FL490 Conjugate

Our Anti-THIK-2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N468/37. It detects mouse and rat THIK-2, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Potassium two pore domain channel subfamily K member 12 is encoded by the gene KCNK12. KCNK12 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK12 has not been shown to be a functional channel; however, it may require other non-pore-forming proteins for activity. KCNK12 is highly expressed in the brain. Diseases associated with KCNK12 include Skin Angiosarcoma and Birk-Barel Syndrome.

Short Description

Our Anti-THIK-2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N468/37. It detects mouse and rat THIK-2, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

THIK-2 (Potassium channel subfamily K member 12) (Tandem pore domain halothane-inhibitedpotassium channel 2) (Kcnk12) (MNTK1)

Gene Name

Kcnk12 mntk1

UniProt

Q76M80

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 313-408 (cytoplasmic C-terminus) of mouse THIK-2 (accession number Q76M80) produced recombinantly in E. Coli

Target

THIK-2

Clonality

Monoclonal

Isotype

IgG1

Clone

N468/37

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Ion Channels and Modulators/K+ Channels

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

47 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

IHC Quality Control

1

RRID

AB_2940540

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