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Anti-TALK1 Potassium Channel Antibody

Our Anti-TALK1 potassium channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N466/14. It detects mouse and rat TALK1 potassium channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Product Specifications

Background

Potassium two pore domain channel subfamily K member 16 is encoded by the gene KCNK16. KCNK16 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK16 is an open rectifier which primarily passes outward current under physiological K+ concentrations. KCNK16 is expressed in the pancreas. Diseases associated with KCNK16 include Birk-Barel Syndrome and Maturity-Onset Diabetes of the Young.

Short Description

Our Anti-TALK1 potassium channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N466/14. It detects mouse and rat TALK1 potassium channel, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

MCG5959, isoform CRA_a (Potassium channel, subfamily K, member 16)

Gene Name

Kcnk16 mCG_5959

UniProt

G5E845

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 42-94 (first extracellular loop) and 259-292 (cytoplasmic C-terminus) of mouse TALK1 (accession number G5E845) produced recombinantly in E. Coli

Target

TALK1 potassium channel

Clonality

Monoclonal

Isotype

IgG2a

Clone

N466/14

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Ion Channels and Modulators/K+ Channels

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

30-40 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

Conjugate

Unconjugated

IHC Quality Control

1

RRID

AB_2716263

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