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Anti-Kv9.2 Antibody

Our Anti-Kv9.2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N460/19. It detects mouse and rat Kv9.2, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Product Specifications

Background

Voltage-gated K+ channels are important determinants of neuronal membrane excitability (Pongs, 1999) . Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. Members of the Kv5-Kv11 families code for “silent subunits” that do not express as functional homomultimers. In heterologous expression systems, silent subunits can coassemble with Kv2 and Kv3 subunits and modulate the biophysical characteristics of the latter subunits (Yan L. et al., 2004) .

Short Description

Our Anti-Kv9.2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N460/19. It detects mouse and rat Kv9.2, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

Kv9.2 (Potassium voltage-gated channel subfamily S member 2) (Delayed-rectifier K (+) channelalpha subunit 2) (Kcns20 (KIAA1144)

Gene Name

Kcns2

UniProt

O35174

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 411-477 (cytoplasmic C-terminus) of mouse Kv9.2 (accession number O35174) produced recombinantly in E. Coli

Target

Kv9.2

Clonality

Monoclonal

Isotype

IgG1

Clone

N460/19

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Ion Channels and Modulators/K+ Channels

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

60-80 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

WB Brain Quality Control

1

Conjugate

Unconjugated

RRID

AB_2714205

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