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Anti-Neuropeptide Y Antibody

Our Anti-Neuropeptide Y mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L115/13. It detects human, mouse, and rat Neuropeptide Y, and is purified by Protein A chromatography. It is great for use in AT, IHC, ICC.

Product Specifications

Background

Neuropeptide Y is encoded by the gene NPY. NPY is a member of the NPY family. NPY is a neuropeptide that influences many physiological processes including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. NPY functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. NPY is widely expressed in the central nervous system. Diseases associated with NPY include Eating Disorder and Adjustment Disorder.

Short Description

Our Anti-Neuropeptide Y mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L115/13. It detects human, mouse, and rat Neuropeptide Y, and is purified by protein a chromatography. It is great for use in IHC, ICC, ELISA, AT.

Synonyms

Pro-neuropeptide Y [Cleaved into: Neuropeptide Y (Neuropeptide tyrosine) (NPY) ; C-flanking peptide of NPY (CPON) ]

Gene Name

NPY

UniProt

P01303

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 28-97 (all but signal peptide) of human NPY (accession number P01303) produced recombinantly in E. Coli

Target

Neuropeptide Y

Clonality

Monoclonal

Isotype

IgG2a

Clone

L115/13

Type

Primary Antibody

Applications

IHC, ICC, ELISA, AT

Field of Research

Cell Signaling

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

11 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

Conjugate

Unconjugated

IHC Quality Control

1

RRID

AB_2651168

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