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Anti-Homer1 Antibody FL650 Conjugate

Our Anti-Homer1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L113/130. It detects human, mouse, and rat Homer1, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Homer Scaffold Protein 1 is encoded by the gene HOMER1. Homer1 is a member of the Homer family of dendritic proteins. Homer1 is a postsynaptic density scaffolding protein which binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1, and SHANK3. HOMER1 is expressed in the skeletal muscle, heart, and brain. Diseases associated with HOMER1 include Phelan-Mcdermid Syndrome, bipolar disorder, autism, fragile x syndrome, and pervasive developmental disorder.

Short Description

Our Anti-Homer1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L113/130. It detects human, mouse, and rat Homer1, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Homer protein homolog 1 (Homer-1) (VASP/Ena-related gene up-regulated during seizure and LTP 1) (Vesl-1)

Gene Name

Homer1 Vesl1

UniProt

Q9Z2Y3

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 121-363 (C-terminus) of mouse Homer1 (accession number Q9Z2Y3) produced recombinantly in E. Coli

Target

Homer1

Clonality

Monoclonal

Isotype

IgG1

Clone

L113/130

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Scaffold Proteins

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

50 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

WB Brain Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2940511

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