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Anti-Neuroligin-2 Antibody

Our Anti-Neuroligin-2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L107/39. It detects human and mouse Neuroligin-2, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Product Specifications

Background

Neuroligin2 is encoded by the gene NLGN2. Neuroligin2 is a transmembrane scaffolding protein and cell adhesion molecule. It is involved in cell-cell interactions in neurons and in other cell types. It is expressed in many tissues, including the brain where it is located at the postysynaptic membrane and is involved in regulation of inhibitory synapses, synapse formation and synaptic transmission. Diseases associated with this gene include Pervasive Developmental Disorder and Autism.

Short Description

Our Anti-Neuroligin-2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L107/39. It detects human and mouse Neuroligin-2, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

Neuroligin-2

Gene Name

Nlgn2 Kiaa1366

UniProt

Q69ZK9

Host

Mouse

Reactivity

Human and Mouse

Immunogen

Fusion protein amino acids 700-836 (cytoplasmic C-terminus) of mouse Neuroligin-2 (accession number Q69ZK9) produced recombinantly in E. Coli

Target

Neuroligin-2

Clonality

Monoclonal

Isotype

IgG1

Clone

L107/39

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Cell Adhesion Molecules/ Cell Markers/Neuronal Markers/Synapse Markers/Post-synaptic Markers

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

90-100 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

WB Brain Quality Control

1

Conjugate

Unconjugated

RRID

AB_2651165

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