Anti-IRSp53/BAIAP2 Antibody FL490 Conjugate

Brain-specific angiogenesis inhibitor 1-associated protein 2 or IRSp53/BAIAP2 is encoded by the gene BAIAP2 and is a MAGUK (membrane-associted guanylase kinase homolog) family. BAIAP2 is an adaptor protein which links G-proteins in the membrane to cytoplasmic proteins and is involved in cell processes including regulation of the actin cytoskeleton, neurite growth and the promotion of filipodia formation. Multiple isoforms of BAIAP2 exist with differential tissue expression. Diseases associated with BAIAP2 include Dentatorubral-Pallidoluysian Atrophy and Attention Deficit-Hyperactivity Disorder.

Our Anti-IRSp53/BAIAP2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L117/1. It detects human, mouse, and rat IRSp53/BAIAP2, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI-associated protein 2) (BAI1-associated protein 2) (Protein BAP2) (Fas ligand-associated factor 3) (FLAF3) (Insulin receptor substrate p53/p58) (IRS-58) (IRSp53/58) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53)

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.