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Anti-IRSp53/BAIAP2 Antibody

Our Anti-IRSp53/BAIAP2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L117/1. It detects human, mouse, and rat IRSp53/BAIAP2, and is purified by Protein A chromatography. It is great for use in AT, IHC, ICC, WB.

Product Specifications

Background

Brain-specific angiogenesis inhibitor 1-associated protein 2 or IRSp53/BAIAP2 is encoded by the gene BAIAP2 and is a MAGUK (membrane-associted guanylase kinase homolog) family. BAIAP2 is an adaptor protein which links G-proteins in the membrane to cytoplasmic proteins and is involved in cell processes including regulation of the actin cytoskeleton, neurite growth and the promotion of filipodia formation. Multiple isoforms of BAIAP2 exist with differential tissue expression. Diseases associated with BAIAP2 include Dentatorubral-Pallidoluysian Atrophy and Attention Deficit-Hyperactivity Disorder.

Short Description

Our Anti-IRSp53/BAIAP2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L117/1. It detects human, mouse, and rat IRSp53/BAIAP2, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA, AT.

Synonyms

Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI-associated protein 2) (BAI1-associated protein 2) (Protein BAP2) (Fas ligand-associated factor 3) (FLAF3) (Insulin receptor substrate p53/p58) (IRS-58) (IRSp53/58) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53)

Gene Name

BAIAP2

UniProt

Q9UQB8

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 1-250 (N-terminus) of human BAIAP2 (accession number Q9UQB8) produced recombinantly in E. Coli

Target

IRSp53/BAIAP2

Clonality

Monoclonal

Isotype

IgG1

Clone

L117/1

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA, AT

Field of Research

Cell Signaling/Cytoskeletal Regulation/G Protein Signaling

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

50-60 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

WB Dilution

1:100

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

WB Brain Quality Control

1

Conjugate

Unconjugated

RRID

AB_2651164

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