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Anti-Kv11.3 Potassium Channel Antibody FL650 Conjugate

Selected Variant

75-440-FL650

Size: 200 µL

Our Anti-Kv11.3 potassium channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N447/24. It detects human, mouse, and rat Kv11.3 potassium channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

ERG3 (ether-a-go-go–related gene 3), Potassium voltage-gated channel subfamily H member 7, or Kv11.3 potassium channel is encoded by the gene Kcnh7 and is a member of the ERG family of voltage activated potassium channels. Kv11.3 is a pore forming, alpha subunit of the potassium channel. Erg channels play roles in regulating the resting membrane potential and action potential duration. Kv11.3 is detected in total brain, in superior cervical, mesenteric and celiac ganglia, and at very low levels in retina and is also found in pituitary.

Short Description

Our Anti-Kv11.3 potassium channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N447/24. It detects human, mouse, and rat Kv11.3 potassium channel, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3) (ERG-3) (Eag-related protein 3) (Ether-a-go-go-related protein 3) (Voltage-gated potassium channel subunit Kv11.3)

Gene Name

Kcnh7 Erg3

UniProt

O54852

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 894-1059 (cytoplasmic C-terminus) of rat Kv11.3 (accession number O54852) produced recombinantly in E. Coli

Target

Kv11.3 potassium channel

Clonality

Monoclonal

Isotype

IgG2b

Clone

N447/24

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Ion Channels and Modulators/K+ Channels

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

120 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

WB Brain Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2940467

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