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Anti-ADAM11 Antibody FL650 Conjugate

Our Anti-ADAM11 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N441/35. It detects mouse and rat ADAM11, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Disintegrin and metalloproteinase domain-containing protein 11, Metalloproteinase-Like, Disintegrin-Like, Cysteine-Rich Protein, or ADAM11 is encoded by the gene ADAM11 and a member of the ADAM (a disintegrin and metalloproteinase) family. ADAM11 is a single-pass type I membrane protein without catalytic metalloprotease-like properties. It is thought to be a ligand for integrin in the brain. ADAM11 is also weakly detected in the heart, liver and testis.

Short Description

Our Anti-ADAM11 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N441/35. It detects mouse and rat ADAM11, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Disintegrin and metalloproteinase domain-containing protein 11 (ADAM 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC)

Gene Name

Adam11 Mdc

UniProt

Q9R1V4

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 243-441 (extracellular domain) of mouse ADAM11 (accession number Q9R1V4) produced recombinantly in E. Coli

Target

ADAM11

Clonality

Monoclonal

Isotype

IgG2b

Clone

N441/35

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Cell Adhesion Molecules

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

75 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with ADAM22

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

WB Brain Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2940439

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