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Anti-ATAT1 Antibody FL650 Conjugate

Our Anti-ATAT1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N347/42. It is KO validated, detects human, mouse, and rat ATAT1, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Alpha-tubulin N-acetyltransferase 1 or ATAT is encoded by the gene ATAT1 and is an enzyme which belongs to the acyltransferase family. ATAT1 functions to acetylate alpha tubulin at Lysine 40. ATAT1 is thought to be involved in microtubule growth, for instance during chemotaxis and the formation of cilium. ATAT1 exists in multiple isotypes. ATAT1 is expressed in many tissues including brain, kidney, retina and testis. Diseases associated with ATAT1 include Von Willebrand Disease, Type 3 and Blood Coagulation Disease.

Short Description

Our Anti-ATAT1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N347/42. It is KO validated, detects human, mouse, and rat ATAT1, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Alpha-tubulin N-acetyltransferase 1 (Alpha-TAT) (Alpha-TAT1) (TAT) (EC 2.3.1.108) (Acetyltransferase mec-17 homolog)

Gene Name

ATAT1 C6orf134 MEC17 Nbla00487

UniProt

Q5SQI0

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 2-236 (N-acetyltransferase domain) of human ATAT1 (accession number Q5SQI0) produced recombinantly in E. Coli

Target

ATAT1

Clonality

Monoclonal

Isotype

IgG1

Clone

N347/42

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Rare Diseases

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

40-45 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

WB Brain Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2940419

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