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Anti-GluN3A/NR3A Antibody FL490 Conjugate

Our Anti-GluN3A/NR3A mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N416/40. It detects mouse and rat GluN3A/NR3A, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Glutamate receptor ionotropic, NMDA3A, N-Methyl-D-Aspartate Receptor Subtype 3A or GluN3A is encoded by the gene GRIN3A. GluN3A is a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of channel forming ionotropic glutamate receptor which is permeable to cations including calcium, potassium and sodium. GluN3a is expressed in the CNS especially in development and appears to play a role in delaying synapse maturation. Diseases associated with GRIN3A include Macrodactyly

Short Description

Our Anti-GluN3A/NR3A mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N416/40. It detects mouse and rat GluN3A/NR3A, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Glutamate receptor ionotropic, NMDA3A

Gene Name

Grin3a

UniProt

A2AIR5

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 58-87 or 152-176 (extracellular N-terminus) of mouse GluN3A (accession number A2AIR5) produced recombinantly in E. Coli

Target

GluN3A/NR3A

Clonality

Monoclonal

Isotype

IgG2a

Clone

N416/40

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Neurotransmitter Receptors

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

110 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

ICC Quality Control

1

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

RRID

AB_2940380

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