What is the catalog number for Anti-GluN2C/NR2C Antibody?

The catalog number for Anti-GluN2C/NR2C Antibody is 75-411.

What sizes are available for Anti-GluN2C/NR2C Antibody?

Anti-GluN2C/NR2C Antibody is available in the following size(s): 100 µL.

Is Anti-GluN2C/NR2C Antibody in stock?

Anti-GluN2C/NR2C Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Anti-GluN2C/NR2C Antibody

Our Anti-GluN2C/NR2C mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N422/18. It is KO validated, detects human, mouse, and rat GluN2C/NR2C, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Product Specifications

Background

Glutamate receptor ionotropic, NMDA 2C, Nmethyl D-aspartate receptor subtype 2C, or GluN2C/NR2C is encoded by the gene GRIN2C. GluN2C is a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of channel forming ionotropic glutamate receptor which is permeable to cations including calcium, potassium and sodium. GluN2C is found in the central nervous system and the cerebellum. GluN2C is thought to have an important role in physiological processes such as learning, memory, and synaptic development. Diseases associated with this gene include Alzheimer disease, Parkinson’s disease and Schizophrenia.

Short Description

Our Anti-GluN2C/NR2C mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N422/18. It is KO validated, detects human, mouse, and rat GluN2C/NR2C, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

Glutamate receptor ionotropic, NMDA 2C (GluN2C) (Glutamate [NMDA] receptor subunit epsilon-3) (N-methyl D-aspartate receptor subtype 2C) (NMDAR2C) (NR2C)

Gene Name

Grin2c

UniProt

Q00961

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 836-1233 (cytoplasmic C-terminus) of rat GluN2C (accession number Q00961) produced recombinantly in E. Coli

Target

GluN2C/NR2C

Clonality

Monoclonal

Isotype

IgG1

Clone

N422/18

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Neurotransmitter Receptors

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

130 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

WB Dilution

1:1000

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.