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Anti-KChIP4 K+ channel Antibody FL550 Conjugate

Our Anti-KChIP4 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N423/75. It is KO validated, detects human, mouse, and rat KChIP4 K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Potassium voltage-gated channel interacting protein 4 is encoded by the gene KCNIP4. KCNIP4 is a member of the recoverin family. KCNIP4 is a regulatory subunit of Kv4/D (Shal) -type voltage-gated rapidly inactivating A-type potassium channels.KCNIP4 modulates KCND2 channel density, inactivation kinetics, and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. KCNIP4 is expressed in brain and bone marrow. Diseases associated with KCNIP4 include Synovial Angioma and Childhood Malignant Schwannoma.

Short Description

Our Anti-KChIP4 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N423/75. It is KO validated, detects human, mouse, and rat KChIP4 K+ channel, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Calsenilin-like protein) (Potassium channel-interacting protein 4)

Gene Name

KCNIP4 CALP KCHIP4

UniProt

Q3YAB7

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 1-233 (full-length) of human KChIP4 (accession number Q3YAB7) produced recombinantly in E. Coli.

Target

KChIP4 K+ channel

Clonality

Monoclonal

Isotype

IgG2a

Clone

N423/75

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Ion Channels and Modulators/K+ Channels

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

30 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with KChIP1, KChIP2 or KChIP3

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

WB Brain Quality Control

1

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

RRID

AB_2940341

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