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Anti-Arx Antibody FL550 Conjugate

Our Anti-Arx mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N411/51. It is KO validated, detects mouse and rat Arx, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Homeobox protein ARX, Aristaless-related homeobox or ARX is encoded by the gene ARX and is a member of the group-II aristaless-related protein family. ARX functions as a transcription factor and is thought to be involved in normal CNS development. ARX is expressed in brain and pancreas during development. Diseases associated with ARX include Early Infantile Epileptic Encephalopathy and X-linked Lissencephaly.

Short Description

Our Anti-Arx mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N411/51. It is KO validated, detects mouse and rat Arx, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Homeobox protein ARX (Aristaless-related homeobox)

Gene Name

Arx

UniProt

O35085

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 1-220 (N-terminus) of mouse Arx (accession number O35085) produced recombinantly in E. Coli

Target

Arx

Clonality

Monoclonal

Isotype

IgG1

Clone

N411/51

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Neurogenesis and Development/Transcription Regulation

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

70 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

IHC Dilution

1:500

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

ICC Quality Control

1

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

RRID

AB_2940325

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