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Anti-SUR2B Antibody

Our Anti-SUR2B mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N323B/20. It detects human, mouse, and rat SUR2B, and is TC supernatant. It is great for use in IHC, ICC, WB.

Product Specifications

Background

Sulfonylurea receptor 2B (SUR2A), or ATP binding cassette transporter subfamily C member 9 is encoded by the gene ABCC9 and is a member of the ABC transporter super family. Differential splicing of the ABCC9 gene produces 2 isoforms, SUR2A and SUR2B. SUR2b forms smooth muscle KATP channels with KCNJ8 (Kir6.1) and is is involved in regulation and activation. It is also expressed in brain. Diseases associated with this gene include Cantu Syndrome and Dilated Cardiomyopathy 1O.

Short Description

Our Anti-SUR2B mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N323B/20. It detects human, mouse, and rat SUR2B, and is tc supernatant. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

ATP-binding cassette sub-family C member 9 (Sulfonylurea receptor 2)

Gene Name

Abcc9 Sur2

UniProt

Q63563-2

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 1503-1545 (VHTILTADLVIVMKRGNILEYDTPESLLAQEDGVFASFVRA DM, cytoplasmic C-terminus) of rat SUR2B (accession number Q63563-2) produced recombinantly in E. Coli

Target

SUR2B

Clonality

Monoclonal

Isotype

IgG2b

Clone

N323B/20

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Ion Channels and Modulators/Ion Channel Modulators

Concentration

Lot dependent

Format

TC Supernatant

Buffer

Supernatant is provided in cell culture medium with 0.1% sodium azide as anti-microbial

Molecular Weight

175 kDa (and smaller fragments likely due to proteolytic cleavage)

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Supernatant is harvested from hybridoma cells grown under standard cell culture conditions

Specificity

Does not cross-react with SUR1

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

ICC Quality Control

1

Conjugate

Unconjugated

RRID

AB_2341102

Frequently Asked Questions

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