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Anti-Kv3.2 Potassium Channel Antibody FL594 Conjugate

Our Anti-Kv3.2 potassium channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N410/17. It is KO validated, detects human, mouse, and rat Kv3.2 potassium channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Potassium voltage-gated channel subfamily C member 2 or Kv3.2 potassium channel, is a member of the potassium channel, voltage-gated, shaker-related subfamily and the Shaw subfamily (the family includes 4 members Kv3.1-Kv3.4) . Kv3.2 is primarily expressed in brain and found in the cortex and hippocampus. It has also been detected in the thalamus and caudate nucleus. Kv3.2 is a membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Diseases associated with KCNC2 include Spinocerebellar Ataxia 13 and Episodic Ataxia, Type 2

Short Description

Our Anti-Kv3.2 potassium channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N410/17. It is KO validated, detects human, mouse, and rat Kv3.2 potassium channel, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Potassium voltage-gated channel subfamily C member 2 (Potassium channel voltage-gated Shaw-related subfamily C member 2) (Shaw-like potassium channel) (Voltage-gated potassium channel subunit Kv3.2)

Gene Name

Kcnc2

UniProt

P22462-3

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 474-613 (cytoplasmic C-terminus) of rat Kv3.2a (accession number P22462-3) produced recombinantly in E. Coli

Target

Kv3.2 potassium channel

Clonality

Monoclonal

Isotype

IgG1

Clone

N410/17

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Ion Channels and Modulators/K+ Channels

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

80-100 kDa (varies due to post-translational modifications)

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

WB Brain Quality Control

1

ICC Quality Control

1

Conjugate

FL594 Ex: 594 nm, Em: 615 nm

RRID

AB_2940310

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