Enpp-1-IN-24
Product Specifications
UNSPSC Description
Enpp-1-IN-24 (compund 7) is an ENPP1 inhibitor that, in combination with anti-PD-1 antibodies, achieves 77.7% tumor growth inhibition and improves survival in mouse models[1].
Target Antigen
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/enpp-1-in-24.html
Smiles
O=C(C1=CN2C(C(C3=C(OC)C=CC=C3F)=N1)=NC=C2)NC4=CC(F)=CC=C4N5CCC(NS(=O)(N)=O)CC5
Molecular Weight
557.57
References & Citations
[1]https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c01634
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168147/Enpp-1-IN-24-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168147/
Clinical Information
No Development Reported
Curated Selection
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