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Anti-CLN3 Antibody

Our Anti-CLN3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N380/87. It detects human CLN3, and is TC supernatant. It is great for use in ICC, WB.

Product Specifications

Background

Ceroid-lipofuscinosis neuronal protein 3, Battenin or CLN3 is encoded by the gene CLN3 and is a member of the CLN protein family. CLN3 is thought to be involved in intracellular trafficking and lysosomal function. Mutations in a CLN related gene can result in neuronal ceroid lipofuscinoses or Batten disease, a group of rare, often fatal lysosomal storage diseases. CLN3 plays a role in the transport of late endosomes and lysosomes. CLN3 is widely expressed in tissues

Short Description

Our Anti-CLN3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N380/87. It detects human CLN3, and is tc supernatant. It is great for use in WB, ICC, ELISA.

Synonyms

Battenin (Batten disease protein) (Protein CLN3)

Gene Name

CLN3 BTS

UniProt

Q13286

Host

Mouse

Reactivity

Human

Immunogen

Fusion protein amino acids 1-37, 59-98, 149-179, 233-277, 299-357 and 379-406 (non-helical domains) of human CLN3 (accession number Q13286) produced recombinantly in E. Coli

Target

CLN3

Clonality

Monoclonal

Isotype

IgG1

Clone

N380/87

Type

Primary Antibody

Applications

WB, ICC, ELISA

Field of Research

Rare Diseases

Concentration

Lot dependent

Format

TC Supernatant

Buffer

Supernatant is provided in cell culture medium with 0.1% sodium azide as anti-microbial

Molecular Weight

55 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Supernatant is harvested from hybridoma cells grown under standard cell culture conditions

Specificity

Does not cross-react with other CLN proteins

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

Unconjugated

RRID

AB_2336902

Frequently Asked Questions

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