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Anti-CLN6 Antibody

Our Anti-CLN6 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N400/24. It detects human CLN6, and is TC supernatant. It is great for use in ICC, WB.

Product Specifications

Background

Ceroid-lipofuscinosis neuronal protein 6 or CLN6 is encoded by the gene CLN6 and is a member of the CLN protein family. CLN6 is thought to be involved in intracellular trafficking and lysosomal function. Mutations in a CLN related gene can result in neuronal ceroid lipofuscinoses or Batten disease, a group of rare, often fatal lysosomal storage diseases. CLN is thought to be involved in the degradation of proteins in lysosomes. CLN6 is widely expressed in tissues and found in the endoplasmic reticulum.

Short Description

Our Anti-CLN6 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N400/24. It detects human CLN6, and is tc supernatant. It is great for use in WB, ICC, ELISA.

Synonyms

Ceroid-lipofuscinosis neuronal protein 6 (Protein CLN6)

Gene Name

CLN6

UniProt

Q9NWW5

Host

Mouse

Reactivity

Human

Immunogen

Fusion protein amino acids 2-55, 131-177 and 281-311 (non-helical domains) of human CLN6 (accession number Q9NWW5) produced recombinantly in E. Coli

Target

CLN6

Clonality

Monoclonal

Isotype

IgG2b

Clone

N400/24

Type

Primary Antibody

Applications

WB, ICC, ELISA

Field of Research

Rare Diseases

Concentration

Lot dependent

Format

TC Supernatant

Buffer

Supernatant is provided in cell culture medium with 0.1% sodium azide as anti-microbial

Molecular Weight

40 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Supernatant is harvested from hybridoma cells grown under standard cell culture conditions

Specificity

Does not cross-react with other CLN proteins

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

Unconjugated

RRID

AB_2336903

Frequently Asked Questions

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