Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-GABA-A-R-Alpha4 Antibody

Our Anti-GABA-A-R-Alpha4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N398A/34. It detects mouse and rat GABA-A-R-Alpha4, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Product Specifications

Background

Gamma-aminobutyric acid receptor subunit alpha-4 or GABA AR alpha4 is encoded by the gene GABRA4. GABAA receptors are members of the Cys-loop family of ligand-gated ion channels. GABA AR alpha 4 is a subunit of the pentameric GABA receptors where GABA is the major inhibitory neurotransmitter in the vertebrate brain and mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel. GABA AR alpha 4 has been found to be expressed in skeletal muscle tissue, adult mammalian kidney, heart and primarily in brain at the cell junction, synapse, and the postsynaptic cell membrane. Disorders involving the GABRA4 gene include autism, Status Epilepticus and restless legs syndrome.

Short Description

Our Anti-GABA-A-R-Alpha4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N398A/34. It detects mouse and rat GABA-A-R-Alpha4, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

Gamma-aminobutyric acid receptor subunit alpha-4 (GABA (A) receptor subunit alpha-4)

Gene Name

Gabra4

UniProt

P28471

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 410-450 (cytoplasmic C-terminus) of rat GABA-A-R-Alpha4 (accession number P28471) produced recombinantly in E. Coli

Target

GABA-A-R-Alpha4

Clonality

Monoclonal

Isotype

IgG1

Clone

N398A/34

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Neurotransmitter Receptors

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

60 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

IHC Dilution

1:250

WB Dilution

1:500

Specificity

Does not cross-react with other GABA-A receptor Alpha subunits

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

WB Brain Quality Control

1

Conjugate

Unconjugated

RRID

AB_2341108

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Mouse Cnbp activation kit by CRISPRa
GA200782 1 Kit

Mouse Cnbp activation kit by CRISPRa

Sign In for Pricing
View Details
Slco1a1 Mouse Gene Knockout Kit (CRISPR)
KN516220 1 Kit

Slco1a1 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
Spc24 Mouse Gene Knockout Kit (CRISPR)
KN516571 1 Kit

Spc24 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
Prohibitin (Mitochondrial Marker) (PHB/3226), CF405S conjugate, 0.1mg/mL
BNC043226-500 1x 500 µL

Prohibitin (Mitochondrial Marker) (PHB/3226), CF405S conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Ep-CAM / CD326 (323/A3), 1mg/mL
BNUM0396-50 1x 50 µL

Ep-CAM / CD326 (323/A3), 1mg/mL

Sign In for Pricing
View Details
Tas2r138 Mouse Gene Knockout Kit (CRISPR)
KN517219 1 Kit

Tas2r138 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details