EphB2, Human (HEK293, Fc)

EphB2 Protein is a neurotrophic factor, and a member of the eph receptor tyrosine kinase. EphB2 plays an important role in cancer progression and in immunity. EphB2 can bind to directly to the NMDA receptor and induces its tyrosine phosphorylation. EphB2 is essential for neuronal connectivity and plasticity in the brain, as well as synaptic function. Besides, EphB2 can also interact with cells expressing ephrinB ligands, and results in EphB2 activation and phosphorylation of tyrosines in the ephrinB cytodomain. EphB2 also regulates thrombus formation and clot retraction[1][2][3][4][5]. EphB2 Protein, Human (HEK293, Fc) is the recombinant human-derived EphB2 protein, expressed by HEK293 , with C-hFc labeled tag.