What is the catalog number for Anti-Beta4-Spectrin Antibody?

The catalog number for Anti-Beta4-Spectrin Antibody is 75-377-020.

What sizes are available for Anti-Beta4-Spectrin Antibody?

Anti-Beta4-Spectrin Antibody is available in the following size(s): 20 µL.

Is Anti-Beta4-Spectrin Antibody in stock?

Anti-Beta4-Spectrin Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Anti-Beta4-Spectrin Antibody

Our Anti-Beta4-spectrin mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N393/76. It detects human, mouse, and rat Beta4-spectrin, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Product Specifications

Background

Spectrin beta chain, non-erythrocytic 4, or ß4 spectrin, is a member of the spectrin family of cytoskeletal proteins. It is found in the cytoskeleton and cell cortex of cells in the brain and pancreatic islets. It is also expressed in skeletal muscule. ß4 spectrin functions as a scaffold protein that links the actin cytoskeleton to the plasma membrane. It is involved in cell shape and organization. Mutations in the ß4 spectrin gene are associated with congenital myopathy, and neurodevelopmental disorder with hypotonia, neuropathy and deafness (NEDHND) .

Short Description

Our Anti-Beta4-spectrin mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N393/76. It detects human, mouse, and rat Beta4-spectrin, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

Spectrin beta chain, non-erythrocytic 4 (Beta-IV spectrin) (Spectrin, non-erythroid beta chain 3)

Gene Name

SPTBN4 KIAA1642 SPTBN3

UniProt

Q9H254

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 1621-1832 (C-terminal repeats 14 to 15) of human Beta4-spectrin (accession number Q9H254) produced recombinantly in E. Coli

Target

Beta4-spectrin

Clonality

Monoclonal

Isotype

IgG2b

Clone

N393/76

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Axonal Markers/Scaffold Proteins

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

>200 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

IHC Dilution

1:250

WB Dilution

1:1000

Specificity

Does not cross-react with other Beta-spectrins

ICC Dilution

1:500

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

Trial Size

Conjugate

Unconjugated

IHC Quality Control

RRID

AB_2315818

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

HR-10035 5 L

BioDil-Diff

View Details

FB151321 0.5 Kg

N-[2-[ (2-Bromo-4,6-dinitrophenyl) azo]-5- (diethylamino) phenyl]acetamide

View Details

sc-416285-NIC 20 µg

ALF Double Nickase Plasmid (h)

View Details

MBS064952 Inquire

Donkey Proteinase 3 Antibody ELISA Kit

View Details

bs-5411R 100 µL

Phospho-MEK1 (Ser385) Polyclonal Antibody

View Details

orb2453117 100 µL

ADAR1 Rabbit Polyclonal Antibody (APC-Cy5.5)

View Details