What is the catalog number for Anti-Beta1-Spectrin Antibody?

The catalog number for Anti-Beta1-Spectrin Antibody is 75-374.

What sizes are available for Anti-Beta1-Spectrin Antibody?

Anti-Beta1-Spectrin Antibody is available in the following size(s): 100 µL.

Is Anti-Beta1-Spectrin Antibody in stock?

Anti-Beta1-Spectrin Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Anti-Beta1-Spectrin Antibody

Our Anti-Beta1-spectrin mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N385/21. It detects human, mouse, and rat Beta1-spectrin, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Product Specifications

Background

Spectrin beta chain, erythrocytic, Beta1 spectrin, or Membrane Cytoskeletal Protein is encoded by the gene SPTB and is a member of the member of the spectrin gene family. Beta1 spectrin is primary member of the cytoskeletal network in the erythrocyte plasma membrane. Beta1 spectrin is involved in cell membrane organization and stability and associates with the proteins band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. Diseases associated with this gene include Spherocytosis and Elliptocytosis.

Short Description

Our Anti-Beta1-spectrin mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N385/21. It detects human, mouse, and rat Beta1-spectrin, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, IP, ELISA.

Synonyms

Spectrin beta chain, erythrocytic (Beta-I spectrin)

Gene Name

SPTB SPTB1

UniProt

P11277

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 1555-2137 (C-terminal repeats 13 to 17) of human Beta1-spectrin (accession number P11277) produced recombinantly in E. Coli

Target

Beta1-spectrin

Clonality

Monoclonal

Isotype

IgG2b

Clone

N385/21

Type

Primary Antibody

Applications

WB, IHC, ICC, IP, ELISA

Field of Research

Cytoskeletal Regulation

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

250 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

IHC Dilution

1:200

WB Dilution

1:1000

IP Dilution

5 μL

Specificity

No cross-reactivity reported

ICC Dilution

1:200

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.