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Anti-Miro2 Antibody FL650 Conjugate

Our Anti-Miro2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N384/63. It detects human and rat Miro2, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Mitochondrial Rho GTPase 2 (Miro2) or Ras Homolog Family Member T2 is encoded by the gene RHOT2 and is a member of the Rho family of GTPases. Miro2 is a mitochondrial GTPase. It is found on the outer mitochondrial membrane and is involved in mitochondrial trafficking. Miro2 is ubiquitously expressed in tissues. Diseases associated with this gene include 3-Methylglutaconic Aciduria and, Autosomal Recessive Congenital Hypomyelinating Neuropathy.

Short Description

Our Anti-Miro2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N384/63. It detects human and rat Miro2, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)

Gene Name

RHOT2 ARHT2 C16orf39

UniProt

Q8IXI1

Host

Mouse

Reactivity

Human and Rat

Immunogen

Fusion protein amino acids 343-580 (second Miro domain) of human Miro2 (accession number Q8IXI1) produced recombinantly in E. Coli

Target

Miro2

Clonality

Monoclonal

Isotype

IgG1

Clone

N384/63

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Cell Signaling/G Protein Signaling/Mitochondrial Biology

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

80 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with Miro1

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

WB Brain Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2940227

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