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Anti-LRRTM2 Antibody FL550 Conjugate

Our Anti-LRRTM2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N209C/35. It is KO validated, detects human, mouse, and rat LRRTM2, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Leucine Rich Repeat Transmembrane Neuronal 2 is encoded by the gene LRRTM2. LRRTM2 is a member of the LRRTM family. LRRTM2 is involved in the development and maintenance of excitatory synapses in the vertebrate nervous system. LRRTM2 regulates surface expression of AMPA receptors and instructs the development of functional glutamate release sites. LRRTM2 is expressed in neuronal tissues. Diseases associated with LRRTM2 include Histrionic Personality Disorder.

Short Description

Our Anti-LRRTM2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N209C/35. It is KO validated, detects human, mouse, and rat LRRTM2, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Leucine-rich repeat transmembrane neuronal protein 2 (Leucine-rich repeat neuronal 2 protein)

Gene Name

LRRTM2 KIAA0416 LRRN2

UniProt

O43300

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Synthetic peptide amino acids 475-489 (MSNMSDQGPYNEYEP, cytoplasmic C-terminus) of human LRRTM2 (accession number O43300)

Target

LRRTM2

Clonality

Monoclonal

Isotype

IgG1

Clone

N209C/35

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Cell Adhesion Molecules

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

80 kDa (and larger due to glycosylation)

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with LRRTM1

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

WB Brain Quality Control

1

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

RRID

AB_2940221

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