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Anti-Shank1 And Shank3 Antibody

Our Anti-Shank1 and Shank3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N367/51. It detects mouse and rat Shank1 and Shank3, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Product Specifications

Background

Shank proteins act as scaffold proteins anchoring and connecting membrane bound receptors and other proteins to the cytoskeleton in neurons to enable cell signaling.

Short Description

Our Anti-Shank1 and Shank3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N367/51. It detects mouse and rat Shank1 and Shank3, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (GKAP/SAPAP-interacting protein) (SPANK-1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP) (Synamon) SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)

Gene Name

Shank1 Shank3 Prosap2

UniProt

Q9JLU4

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 538-626 (SH3 domain) of rat Shank3 (accession number Q9JLU4) produced recombinantly in E. Coli

Target

Shank1 and Shank3

Clonality

Monoclonal

Isotype

IgG2a

Clone

N367/51

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Scaffold Proteins

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

190 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

Cross-reacts with Shank1Does not cross-react with Shank2

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

ICC Quality Control

1

Conjugate

Unconjugated

RRID

AB_2315919

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