ARS-1323
ARS-1323 (Example 30, No. 227) is the racemate of ARS-1620. ARS-1323 is a novel inhibitor of mutant K-ras G12C[1].
Product Specifications
CAS Number
[1698024-73-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ARS-1323.html
Purity
99.67
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C=C)N1CCN(C2=NC=NC3=C2C=C(Cl)C(C4=C(O)C=CC=C4F)=C3F)CC1
Molecular Formula
C21H17ClF2N4O2
Molecular Weight
430.84
Precautions
H302, H315, H319, H335
References & Citations
[1]Liansheng Li, et al. Inhibitors of kras g12c. WO 2015054572 A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras
Available Sizes
Curated Selection
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