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Anti-Kirrel3 Short And Long Antibody FL650 Conjugate

Our Anti-Kirrel3 short and long mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N321C/49. It detects mouse and rat Kirrel3 short and long, and is purified by Protein A chromatography. It is great for use in ICC.

Product Specifications

Background

Kirre Like Nephrin Family Adhesion Molecule 3 is encoded by the gene KIRREL3. KIRREL3 is a member of the immunoglobulin superfamily, nephrin-like protein family. KIRREL3 is a synaptic cell adhesion molecule with multiple extracellular immunoglobulin-like domains and a cytoplasmic PDZ domain-binding motif. KIRREL3 is expressed in brain, bone marrow, and stromal cells. Diseases associated with KIRREL3 include Autosomal Dominant Non-Syndromic Intellectual Disability and Autosomal Dominant Non-Syndromic Intellectual Disability 4.

Short Description

Our Anti-Kirrel3 short and long mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N321C/49. It detects mouse and rat Kirrel3 short and long, and is purified by protein a chromatography. It is great for use in ICC.

Synonyms

Membrane protein KIRRE

Gene Name

Kirrel3 Kirrel3_predicted

UniProt

Q09GS6

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 46-524 (extracellular N-terminus) of rat Kirrel3 (accession number Q09GS6) produced recombinantly in E. Coli

Target

Kirrel3 short and long

Clonality

Monoclonal

Isotype

IgG2b

Clone

N321C/49

Type

Primary Antibody

Applications

ICC

Field of Research

Cell Adhesion Molecules

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

85-105 kDa (multiple isoforms)

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Reacts with Kirrel3 short and long isoformsDoes not cross-react with Kirrel1 and Kirrel2

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

WB Brain Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2940151

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